For Kojima, Jennie simultaneously occupies the roles of lover, teacher, rival, partner, and confidante. He read the novel as more than a moral tale about a bittersweet first love and loss: a story about living, told from a feminine point of view, and about how to pass the baton (his "memes") to the next generation.
Kojima closed his essay by imagining his adolescent reading of Jennie as a dream in which he met a cat. An adult rereading made him realize he had never forgotten that experience and led him to correct his initial claim that he had never had a cat: in an intimate sense he had had Jennie and continued to carry her meme inside him.
Thirty-three years after his youthful reading, Kojima took Jennie from his bookshelf again. Upon rereading it he discovered that the cat had influenced not only his view of women but also his creative work.
Kojima saw the Kenzie & Gennaro novels as more than a detective series: in a setting of violence, poverty, pain, and an apparent lack of a future, he cared that the characters kept struggling to live, and he considered that combination an expression of storytelling at its core.
Kojima attributed Jennie as a subconscious inspiration for The Boss in Metal Gear Solid 3. He framed the opposition of Snake as a stray dog and The Boss as a mother cat in terms of his intention to introduce motherhood and the point of view of stray cats into a saga he had until then regarded as a story of parricide led by war dogs.
Kojima said he entered high school unable to tell dogs from cats because he had never had either as a pet; not for lack of wanting one, but because his mother suffered from asthma. In his first summer of high school he picked Jennie by Paul Gallico despite not being a cat lover, and he suspected the title might have reminded him of Jaime Sommers from The Bionic Woman.